硕士生导师简介

张健 专业学科：生物化学与分子生物学 研究方向：植物分子生物学与基因工程

张健，男，汉族，湖南宁远人，1979年生，理学博士，现为中国水稻所研究员。主要研究方向为：

1. 水稻生殖发育相关基因的克隆与功能研究。

2. 蛋白质翻译后修饰在水稻生殖发育中的调控机理。

工作经历

2013年7月至今：中国水稻研究所研究员。

2011年11月至2013年6月：美国密西西比州立大学生物化学，分子生物学，植病与昆虫系助理研究教授（Assistant Research Professor）。

2008年1月至2011年11月：美国密西西比州立大学生物化学与分子生物学系博士后研究员（Postdoctoral Research Associate）。

教育背景

2001年9月至2007年10月：华中农业大学作物遗传改良国家重点实验室，生物化学与分子生物学专业硕博连读研究生，获理学博士学位。

1997年9月至2001年6月： 湖南农业大学植物科技学院农学专业本科生，获农学学士学位。

已发表论文（*corresponding author）

1. Wang, Y., Hou, Y., Qiu, J., Li, Z., Zhao, J., Tong, X. and Zhang, J*. (2017) A Quantitative Acetylomic Analysis of Early Seed Development in Rice (Oryza sativa L.). International journal of molecular sciences, 18, 1376.

2. Hou, Y., Qiu, J., Wang, Y., Li, Z., Zhao, J., Tong, X., Lin, H. and Zhang, J*. (2017) A quantitative proteomic analysis of brassinosteroid-induced protein phosphorylation in rice (Oryza sativa L.). Frontier in Plant Science. 8, 514.

3. Wang, Y.; Tong, X.; Qiu, J.; Li, Z.; Zhao, J.; Hou, Y., Tang, L. and Zhang, J*. (2017) A phosphoproteomic landscape of rice (Oryza sativa L.) tissues.  Physiologia Plantarum. DOI: 10.1111/ppl.12574.

4. Ying, J.; Zhao, J.; Hou, Y.; Wang, Y.; Qiu, J.; Li, Z.; Tong, X.; Shi, Z.; Zhu, J. and Zhang, J*. (2017) Mapping the N-linked glycosites of rice (Oryza sativa L.) germinating embryos. PloS one, 12, (3), e0173853.

5. Qiu, J., Hou, Y., Wang, Y., Li, Z., Zhao, J., Tong, X., Lin, H., Wei, X., Ao, H. and Zhang, J*. (2017) A comprehensive proteomic survey of ABA-induced protein phosphorylation in rice (Oryza sativa L.). International Journal of Molecular Sciences, 18, 60.

6. Li, Z., Tang, L., Qiu, J., Zhang, W., Wang, Y., Tong, X., Wei, X., Hou, Y. and Zhang, J*. (2016) Serine carboxypeptidase 46 Regulates Grain Filling and Seed Germination in Rice (Oryza sativa L.). PloS one, 11, e0159737.

7. Qiu, J., Hou, Y., Tong, X., Wang, Y., Lin, H., Liu, Q., Zhang, W., Li, Z., Nallamilli, B.R. and Zhang, J*. (2016) Quantitative phosphoproteomic analysis of early seed development in rice (Oryza sativa L.). Plant molecular biology, 90, 249-265.

8. Hou, Y., Qiu, J., Tong, X., Wei, X., Nallamilli, B.R., Wu, W., Huang, S*. and Zhang, J*. (2015) A comprehensive quantitative phosphoproteome analysis of rice in response to bacterial blight. BMC plant biology, 15, 163.

9. Hou, Y., Wang, L., Wang, L., Liu, L., Li, L., Sun, L., Rao, Q., Zhang, J*. and Huang, S*. (2015) JMJ704 positively regulates rice defense response against Xanthomonas oryzae pv. oryzae infection via reducing H3K4me2/3 associated with negative disease resistance regulators. BMC plant biology, 15, 286.

10. Chen, Z., Gao, X. and Zhang, J. (2015) Alteration of osa-miR156e expression affects rice plant architecture and strigolactones (SLs) pathway. Plant cell reports, 34, 767-781.

11. Nallamilli, B.R., Edelmann, M.J., Zhong, X., Tan, F., Mujahid, H., Zhang, J., Nanduri, B. and Peng, Z. (2014) Global analysis of lysine acetylation suggests the involvement of protein acetylation in diverse biological processes in rice (Oryza sativa). PloS one, 9, e89283.

12. Zhang, J., Mujahid, H., Hou, Y., Nallamilli, B.R. and Peng, Z. (2013) Plant long non-coding RNA: a new frontier of gene regulation. 2013. American Journal of Plant Sciences. American Journal of Plant Sciences, 4, 1038-1045.

13. Mujahid, H., Tan, F., Zhang, J., Nallamilli, B.R., Pendarvis, K. and Peng, Z. (2013) Nuclear proteome response to cell wall removal in rice (Oryza sativa). Proteome science, 11, 26.

14. Nallamilli, B.R., Zhang, J., Mujahid, H., Malone, B.M., Bridges, S.M. and Peng, Z. (2013) Polycomb group gene OsFIE2 regulates rice (Oryza sativa) seed development and grain filling via a mechanism distinct from Arabidopsis. PLoS genetics, 9, e1003322.

15. Yang, J., Wang, J., Fan, J., Zhu, J.Y., Chen, T., Wang, C.L., Zheng, T.Q., Zhang, J. and Zhong, W.G. (2013) Development of AS-PCR marker based on a key mutation confirmed by re-sequencing of Wx-mp in Milk Princess and its application in japonica soft rice (Oryza sativa L.) breeding. Plant Breeding, 132, 595-603.

16. Gao, X., Chen, Z., Zhang, J., Li, X., Chen, G., Li, X. and Wu, C. (2012) OsLIS-L1 encoding a lissencephaly type-1-like protein with WD40 repeats is required for plant height and male gametophyte formation in rice. Planta, 235, 713-727.

17. Zhang, J., Nallamilli, B.R., Mujahid, H. and Peng, Z. (2010) OsMADS6 plays an essential role in endosperm nutrient accumulation and is subject to epigenetic regulation in rice (Oryza sativa). The Plant journal, 64, 604-617.

18. Zhang, J#., Guo, D#., Chang, Y., You, C., Li, X., Dai, X., Weng, Q., Zhang, J., Chen, G., Li, X., Liu, H., Han, B., Zhang, Q. and Wu, C. (2007) Non-random distribution of T-DNA insertions at various levels of the genome hierarchy as revealed by analyzing 13 804 T-DNA flanking sequences from an enhancer-trap mutant library. The Plant journal, 49, 947-959.

课题资助

中国水稻研究所“青年英才计划”启动基金，100万元，主持，2013-2014。

中国农科院科技创新工程“水稻生殖发育生物学团队”，380万元，主持，2014-2016。

国家自然科学基金青年基金，项目号：31401366，24万元，主持，2015-2017。

中国农科院科技创新工程“青年英才计划”，300万元，主持，2015-2018。

社会活动与任职

中国农科院农业科技创新工程“水稻生殖发育生物学”创新团队首席专家。

受邀为The plant biotechnology journal, Molecular Plant, Plos One, Acta Physiologiae Plantarum, Archives of Enviromental Contamination and Toxicology, Journal of Data Mining in Genomics & Proteomics 等多家主流杂志审稿逾20篇。

通讯地址：浙江省富阳市水稻所路28号 中国水稻研究所 311400

电　　话：0571-63370277, 15382353269

电子邮箱：[email protected]