硕士生导师简介
张健 专业学科:生物化学与分子生物学 研究方向:植物分子生物学与基因工程 |
张健,男,汉族,湖南宁远人,1979年生,理学博士,现为中国水稻所研究员。主要研究方向为:
1. 水稻生殖发育相关基因的克隆与功能研究。
2. 水稻生殖发育相关的表观遗传调控基因的功能研究。
3. 蛋白质翻译后修饰在水稻生殖发育中的调控机理。
工作经历
2013年7月至今:中国水稻研究所研究员。
2011年11月至2013年6月:美国密西西比州立大学生物化学,分子生物学,植病与昆虫系助理研究教授(Assistant Research Professor)。
2008年1月至2011年11月:美国密西西比州立大学生物化学与分子生物学系博士后研究员(Postdoctoral Research Associate)。
教育背景
2001年9月至2007年10月:华中农业大学作物遗传改良国家重点实验室,生物化学与分子生物学专业硕博连读研究生,获理学博士学位。
1997年9月至2001年6月: 湖南农业大学植物科技学院农学专业本科生,获农学学士学位。
近期发表的主要论文
1. JiehuaQiu, YuxuanHou, Xiaohong Tong Yifeng Wang, Haiyan Lin, Qing Liu, Wen Zhang, Babi R. Nallamilli, Jian Zhang*. Quantitative phosphoproteomic analysis of protein phosphorylation in early seed development of rice (Oryza sativa L.). lant Molecular Biology, 2015. Doi:10.1007/s11103-015-0410-2.
2. YuxuanHou, Liyuan Wang, Ling Wang, Lianmeng Liu, Lu li, Lei Sun, QiongRao, Jian Zhang*, Shiwen Huang. JMJ704 positively regulates rice defense response against Xanthomonasoryzaepv. oryzae infection via reducing H3K4me2/3 associated with negative disease resistance regulators. BMC Plant Biology, 2015, 15: 286.
3. Yuxuan Hou, Jiehua Qiu, Xiaohong Tong, Xiangjin Wei, Babi R. Nallamilli, Weihuai Wu, Shiwen Huang and Jian Zhang*. A comprehensive quantitative phosphoproteome analysis of rice in response to bacterial blight. BMC Plant Biology. 2015, 15: 163.
4. Zhihui Chen, Xinqiang Gao, Jian Zhang. Alteration of osa-miR156e expression affects rice plant architecture and strigolactones (SLs) pathway. Plant Cell Reporter, 2015, 34(5): 767-81.
5. Babi Ramesh Reddy Nallamilli., Mariola J. Edelmann., Xiaoxian Zhong1, Feng Tan, Hana Mujahid, Jian Zhang, Bindu Nanduri, Zhaohua Peng. Global Analysis of Lysine Acetylation Suggests the Involvement of Protein Acetylation in Diverse Biological Processes in Rice (Oryza sativa). Plos ONE, 2014, 9:2. e89283.
6. Hana Mujahid, Feng Tan, Jian Zhang, Babi R. Nallamilli, Ken Pendarvis and Zhaohua Peng. Nuclear proteome response to cell wall removal in rice (Oryza sativa). Proteome Science, 2013, 11:26 doi:10.1186/1477-5956-11-26. (近5年影响因子: 2.42)
7. J. Yang, J. Wang, F.J. Fan, J.Y. Zhu, T. Chen, C.L. Wang, T.Q. Zheng, J Zhang, W.G. Zhong. Development of AS-PCR marker based on a key mutation confirmed by re-sequencing of Wx-mp in Milk Princess and its application in japonica soft rice (Oryza sativa L.) breeding. Plant Breeding, 2013, 132, 595–603. (近5年影响因子: 1.18)
8. Jian Zhang, Hana Mujahid, Yuxuan Hou, Babi R. Nallamilli and Zhaohua Peng. Plant long non-coding RNA: a new frontier of gene regulation. Accepted by American Journal of Plant Sciences, 2013, 4:1038-1045.(暂无影响因子)
9. Babi R. Nallamilli, Jian Zhang, Hana Mujahid, Brandon M Malone, Susan M Bridges and Zhaohua Peng. Polycomb Group Gene OsFIE2 Regulates Rice (Oryza sativa) Seed Development and Grain Filling via a Mechanism Distinct from Arabidopsis. Plos Genetics, 2012, 9(3): e1003322. doi:10.1371/journal.pgen.1003322. (近5年影响因子: 10.0)
10. Xinqiang Gao, Zhihui Chen, Jian Zhang, Xingwang Li, Guoxing Chen, Xianghua Li and Changyin Wu. OsLIS-L1 encoding a lissencephaly type-1-like protein with WD40 repeats is required for plant height and male gametophyte formation in rice. Planta, 2011, 235, 713-27. (近5年影响因子: 3.42)
11. Jian Zhang, Babi R. Nallamilli, Hana Mujahid, and Zhaohua Peng. OsMADS6 plays an essential role in endosperm nutrient accumulation and is subject to epigenetic regulation in rice (Oryza sativa). The Plant Journal, 2010, 64, 604-617. (近5年影响因子: 7.121)
12. Jian Zhang, Dong Guo, Yuxiao Chang, Changjun You, Xingwang Li, Xiaoxia Dai, Qijun Weng, Jianwei Zhang, Guoxing Chen, Xianghua Li, et al. Non-random distribution of T-DNA insertions at various levels of the genome hierarchy as revealed by analyzing 13 804 T-DNA flanking sequences from an enhancer-trap mutant library. The Plant Journal, 2007, 49, 947–959. (近5年影响因子: 7.121)
课题资助
中国农科院科技创新工程“青年英才计划”启动基金,1,000,000元,主持,2013-2014.
中国农科院科技创新工程“水稻生殖发育生物学团队”,1,100,000元,主持,2014-2015.
国家自然科学基金青年基金,项目号31401366, 240,000元,主持,2015-2017.
社会活动与任职
中国农科院农业科技创新工程“水稻生殖发育生物学”创新团队首席专家。
受邀为The plant biotechnology journal, Molecular Plant, Plos One, Acta Physiologiae Plantarum, Archives of Enviromental Contamination and Toxicology, Journal of Data Mining in Genomics & Proteomics 等多家主流杂志审稿逾20篇。
通讯地址:浙江省富阳市水稻所路28号中国水稻研究所 311400
电 话:0571-63370277, 13656661382
电子邮箱:zhangjian;caas.cn